SCHEMBL7304936

SCHEMBL7304936

O=P(O)([N]c1ccccc1)Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ANPEP P15144 2/20 0.41
LAP3 P28838 2/20 0.41
KLK8 O60259 2/20 0.41
PLAU P00749 2/20 0.41
KLK2 P20151 2/20 0.41
KLK4 Q9Y5K2 2/20 0.41
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873578 0.74 SRC (0.55) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL8587398 0.74 L3MBTL1 (0.53) SRCL3MBTL1TDP1KDM4EKLK8
SCHEMBL27676341 0.73 SRC (0.73) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL4272051 0.73 SRC (0.73) SRCL3MBTL1TDP1CYP2C9CYP2C19
Phenyl Dihydrogen Phosphate SCHEMBL28311333 0.73 SRC (1.00) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL342310 0.73 CA2 (0.52) SRCCYP2C9CYP2C19PLAUMEN1
SCHEMBL37038 0.73 SRC (0.73) SRCL3MBTL1TDP1CYP2C9CYP2C19
Phenyl Dihydrogen Phosphate SCHEMBL20263 0.73 SRC (1.00) SRCL3MBTL1TDP1CYP2C9CYP2C19
Benzene SCHEMBL11142811 0.73 SRC (0.73) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL6686008 0.73 SRC (0.73) SRCL3MBTL1TDP1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0521827-A1 Pharmacological active hydrazin derivatives and process for their preparation CIBA-GEIGY AG (CH) 1993-01-07 EP disclosed
EP-0111105-B1 UNSATURATED AROMATIC AMIDES AS PESTICIDES THE WELLCOME FOUNDATION LIMITED (GB) 1990-12-05 EP disclosed
EP-0374098-A2 Inhibitors of retroviral proteases CIBA-GEIGY AG (CH) 1990-06-20 EP disclosed
US-4931469-A APPLYING UNSATURATED PHENYL AMIDES; FOR ACARINA BURROUGHS WELLCOME CO. (US) 1990-06-05 US disclosed
EP-0343801-A2 N-(5,6,7,8-tetrahydropyrido(2,3-D)pyrimidin-6-yl-alkanoyl)-glutamic acid derivatives THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1989-11-29 EP disclosed
US-4855086-A MITICIDES, INSECTICIDES BURROUGHS WELLCOME CO. (US) 1989-08-08 US disclosed
EP-0095348-B1 HIGH MOLECULAR WEIGHT POLYBENZIMIDAZOLES CELANESE CORPORATION (US) 1986-04-09 EP disclosed