SCHEMBL873578

SCHEMBL873578

[N-]=[N+]=NP(=O)(O)Oc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
ANPEP P15144 2/20 0.40
LAP3 P28838 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80417 0.82 SRC (0.52) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL2303782 0.82 SRC (0.52) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL27836558 0.82 SRC (0.52) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL25883278 0.79 SRC (0.48) SRCL3MBTL1TDP1ANPEPLAP3
SCHEMBL9911203 0.79 SRC (0.48) SRCL3MBTL1TDP1ANPEPLAP3
SCHEMBL27881894 0.78 SRC (0.47) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL17305220 0.78 L3MBTL1 (0.50) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL2497223 0.78 L3MBTL1 (0.50) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL734215 0.78 SRC (0.61) SRCL3MBTL1TDP1CYP2C9CYP2C19
Phosphoric Acid SCHEMBL29974301 0.78 SRC (0.47) SRCL3MBTL1TDP1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2834224-B1 PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF MSN LAB LTD (IN) 2018-06-06 EP claimed
US-20150087842-A1 Process For The Preparation Of Benzimidazole Derivatives And Salts Thereof MSN LABORATORIES PRIVATE LIMITED (IN) 2015-03-26 US claimed
EP-2834224-A2 PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF MSN Laboratories Limited (IN) 2015-02-11 EP claimed
WO-2014061034-A1 PROCESS FOR PREPARATION OF BOCEPREVIR AND INTERMEDIATES THEREOF MSN LABORATORIES LIMITED (IN) 2014-04-24 WO claimed
WO-2013150545-A2 PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF MSN LABORATORIES LIMITED (IN) 2013-10-10 WO claimed
WO-2011138795-A2 PROCESS FOR PREPARING (S)-10-ACETOXY-10,11-DIHYDRO-5H-DIBENZ[B,F] AZEPINE-5-CARBOXAMIDE MSN LABORATORIES LIMITED (IN) 2011-11-10 WO claimed
EP-0565567-B1 AMIDES OF ANTIBIOTIC GE 2270 FACTORS LEPETIT SPA (IT) 1995-01-18 EP claimed
WO-2023244815-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME MONTE ROSA THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed
EP-2834224-B1 PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF MSN LAB LTD (IN) 2018-06-06 EP disclosed
EP-2294053-B1 GLUCOKINASE ACTIVATORS TAKEDA CALIFORNIA INC (US) 2016-01-06 EP disclosed
EP-2834224-A2 PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF MSN Laboratories Limited (IN) 2015-02-11 EP disclosed
WO-2014061034-A1 PROCESS FOR PREPARATION OF BOCEPREVIR AND INTERMEDIATES THEREOF MSN LABORATORIES LIMITED (IN) 2014-04-24 WO disclosed
EP-2654751-A1 PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF Purdue Pharma L.P. (US) 2013-10-30 EP disclosed
CN-1149085-C Inhibition of RAF kinase with substituted heterocyclic ureas 2004-05-12 CN disclosed
CN-1119343-C Substituted aminocycloalkylpyrrolidine derivatives DAIICHI SEIYAKU CO (JP) 2003-08-27 CN disclosed
CN-1341098-A Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors BAYER AG (US) 2002-03-20 CN disclosed
CN-1064044-C Heterocyclic compounds, their productin and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-04-04 CN disclosed
CN-1040755-C Heterocyclic compounds, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-11-18 CN disclosed
CN-1079966-A Heterogeneous ring compound, its preparation and application TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-29 CN disclosed
CN-1067890-A Heterogeneous ring compound, its preparation and application TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-01-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150087842-A1 Process For The Preparation Of Benzimidazole Derivatives And Salts Thereof AZI2, IL4I1, ABAT SRC 1746/4885L3MBTL1 3779/4885TDP1 4045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.