Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310097 | 1.00 | EBP (0.43) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL5755328 | 0.80 | EBP (0.48) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL5243028 | 0.78 | EBP (0.47) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL7305092 | 0.78 | EBP (0.47) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL7314647 | 0.78 | EBP (0.42) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL7314638 | 0.78 | EBP (0.42) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL7314643 | 0.78 | EBP (0.42) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL7753625 | 0.71 | EBP (0.56) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL5226760 | 0.71 | EBP (0.56) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL7310837 | 0.71 | EBP (0.52) | EBPSIGMAR1CYP3A4CYP2D6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |