Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797234 | 0.85 | THRB (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL819722 | 0.85 | THRB (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL739363 | 0.84 | KDM4E (0.61) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30337649 | 0.84 | KDM4E (0.61) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9346190 | 0.83 | HTT (0.42) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL730512 | 0.83 | KDM4E (0.59) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL19565624 | 0.83 | KMT2A (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8840373 | 0.81 | KDM4E (0.45) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL12245560 | 0.81 | THRB (0.50) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL15302744 | 0.81 | THRB (0.50) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2179007-B1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | DU PONT (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2179007-B1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | DU PONT (US) | 2012-10-17 | — | — | EP | disclosed |
| US-8137582-B2 | Alkaloid monomers, liquid crystal compositions and polymer networks derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-20 | — | — | US | disclosed |
| US-8137582-B2 | Alkaloid monomers, liquid crystal compositions and polymer networks derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-20 | — | — | US | disclosed |
| US-8137582-B2 | Alkaloid monomers, liquid crystal compositions and polymer networks derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-20 | — | — | US | disclosed |
| US-20110193019-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-08-11 | — | — | US | disclosed |
| US-20110193019-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-08-11 | — | — | US | disclosed |
| US-20110193019-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-08-11 | — | — | US | disclosed |
| EP-2179007-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. du Pont de Nemours and Company (US) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009023762-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009023762-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110193019-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | BHMT, BHMT2, NOTUM | MAPT 48/4885KDM4E 4290/4885MEN1 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.