Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305795 | 0.94 | MASP2 (0.39) | MASP2CTSKCTSSLMNAKDM4E | |
| SCHEMBL7311085 | 0.89 | MASP2 (0.37) | MASP2CTSKCTSLCTSSLMNA | |
| Hydrochloric Acid SCHEMBL7311637 | 0.87 | ITGB3 (0.38) | NR1D1 | |
| SCHEMBL9568160 | 0.81 | YAP1 (0.41) | MASP2YAP1LMNAPKMMAPK1 | |
| SCHEMBL7314657 | 0.80 | ITGB3 (0.48) | MASP2CTSKCTSSLMNAL3MBTL1 | |
| SCHEMBL9568161 | 0.78 | BCHE (0.46) | MASP2 | |
| Hydrochloric Acid SCHEMBL7312430 | 0.78 | ITGB3 (0.38) | — | |
| SCHEMBL7310281 | 0.75 | ITGB3 (0.47) | MASP2CTSKCTSLCTSSL3MBTL1 | |
| SCHEMBL7316413 | 0.75 | ITGB3 (0.47) | MASP2CTSKCTSLCTSSL3MBTL1 | |
| SCHEMBL7303107 | 0.74 | ITGB3 (0.46) | MASP2CTSKCTSLCTSSL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |