SCHEMBL7305162

SCHEMBL7305162

C=c1c(=O)[nH]c2n1Cc1c(ccc(OOCCCC(=O)N(C)CC)c1F)N=2

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 8/20 0.46
PDE3A Q14432 8/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7311818 0.83 PDE3B (0.45) PDE3BPDE3A
SCHEMBL7320963 0.77 PDE3B (0.50) PDE3BPDE3A
SCHEMBL7309538 0.74 PDE3B (0.48) PDE3BPDE3A
SCHEMBL7316751 0.72 PDE3B (0.45) PDE3BPDE3A
SCHEMBL7313595 0.71 PDE3B (0.68) PDE3BPDE3A
SCHEMBL7313037 0.69 PDE3B (0.46) PDE3BPDE3A
SCHEMBL7308929 0.69 PDE3B (0.44) PDE3BPDE3A
SCHEMBL7316554 0.68 PDE3B (0.46) PDE3BPDE3A
SCHEMBL7317796 0.68 PDE3B (0.69) PDE3BPDE3A
SCHEMBL7308920 0.68 PDE3B (0.43) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed