Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.56 |
| ▸ | FKBP1A | P62942 | 10/20 | 0.51 |
| ▸ | CMA1 | P23946 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297349 | 0.90 | FKBP1A (0.54) | ELANEFKBP1A | |
| SCHEMBL7309861 | 0.86 | ELANE (0.62) | ELANECMA1ALDH1A1TSHR | |
| SCHEMBL1992452 | 0.84 | FKBP1A (0.60) | ELANEFKBP1ACMA1ALDH1A1CYP3A4 | |
| SCHEMBL18619664 | 0.82 | ELANE (0.60) | ELANEFKBP1ACMA1 | |
| SCHEMBL22209466 | 0.82 | ELANE (0.60) | ELANEFKBP1ACMA1 | |
| SCHEMBL7322912 | 0.81 | FKBP1A (0.52) | FKBP1ACMA1ALDH1A1CYP3A4TSHR | |
| SCHEMBL7322906 | 0.81 | FKBP1A (0.52) | FKBP1ACMA1ALDH1A1CYP3A4TSHR | |
| SCHEMBL22209363 | 0.80 | ALDH1A1 (0.62) | ELANEFKBP1ACMA1ALDH1A1CYP3A4 | |
| SCHEMBL1506200 | 0.80 | ALDH1A1 (0.62) | ELANEFKBP1ACMA1ALDH1A1CYP3A4 | |
| SCHEMBL30051146 | 0.80 | ALDH1A1 (0.62) | ELANEFKBP1ACMA1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494071-B1 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5430025-A | Elastase-inhibiting peptides bearing a C-terminal trifluoromethylketone moiety | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5296591-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0494071-A2 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |