Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103345 | 0.87 | FKBP1A (0.47) | POLBALDH1A1HTTMMP8MMP12 | |
| SCHEMBL9103351 | 0.87 | FKBP1A (0.47) | POLBALDH1A1HTTMMP8MMP12 | |
| SCHEMBL26212073 | 0.84 | FKBP1A (0.51) | POLBALDH1A1HTTMMP8MMP12 | |
| SCHEMBL3256303 | 0.83 | FKBP1A (0.56) | POLBALDH1A1HTTMMP8MMP12 | |
| SCHEMBL3256301 | 0.83 | FKBP1A (0.56) | POLBALDH1A1HTTMMP8MMP12 | |
| SCHEMBL19902090 | 0.83 | SMN1; SMN2 (0.39) | POLBALDH1A1MMP8MMP12MMP13 | |
| SCHEMBL8427907 | 0.83 | SMN1; SMN2 (0.39) | POLBALDH1A1MMP8MMP12MMP13 | |
| SCHEMBL6830972 | 0.82 | FKBP1A (0.58) | POLBMMP8MMP12MMP13 | |
| SCHEMBL6830973 | 0.82 | FKBP1A (0.58) | POLBMMP8MMP12MMP13 | |
| SCHEMBL10552252 | 0.80 | MMP8 (0.45) | POLBMMP8MMP12MMP13ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |