Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | FPR2 | P25090 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | PPID | Q08752 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ANPEP | P15144 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29883935 | 0.86 | CTSK (0.58) | CTSLCTSBCTSSCTSKFPR2 | |
| SCHEMBL29272912 | 0.86 | CTSK (0.58) | CTSLCTSBCTSSCTSKFPR2 | |
| SCHEMBL5098654 | 0.84 | FPR2 (0.76) | CTSLCTSBCTSSCTSKFPR2 | |
| SCHEMBL5098656 | 0.84 | FPR2 (0.76) | CTSLCTSBCTSSCTSKFPR2 | |
| SCHEMBL26606003 | 0.83 | CA12 (0.61) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL26606001 | 0.83 | CA12 (0.61) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL839816 | 0.80 | CTSL (0.59) | CTSLCTSBCTSSCTSKPPID | |
| SCHEMBL838492 | 0.80 | CTSL (0.59) | CTSLCTSBCTSSCTSKPPID | |
| SCHEMBL839616 | 0.80 | CTSL (0.59) | CTSLCTSBCTSSCTSKPPID | |
| SCHEMBL4345272 | 0.79 | PPID (0.48) | FPR2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |