Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314527 | 0.94 | SIGMAR1 (0.42) | SIGMAR1TMEM97ABCB1ALDH1A1MAPT | |
| SCHEMBL7314513 | 0.94 | SIGMAR1 (0.42) | SIGMAR1TMEM97ABCB1ALDH1A1MAPT | |
| SCHEMBL7307029 | 0.92 | ALDH1A1 (0.47) | SIGMAR1TMEM97ABCB1ALDH1A1MAPT | |
| SCHEMBL7314130 | 0.90 | ALDH1A1 (0.43) | SIGMAR1TMEM97ABCB1ALDH1A1MAPT | |
| SCHEMBL7309148 | 0.90 | ACHE (0.47) | — | |
| SCHEMBL7303927 | 0.89 | SIGMAR1 (0.47) | SIGMAR1TMEM97ABCB1ALDH1A1KMT2A | |
| SCHEMBL7311490 | 0.89 | SIGMAR1 (0.42) | SIGMAR1TMEM97ABCB1 | |
| SCHEMBL7317975 | 0.88 | ACHE (0.43) | — | |
| SCHEMBL7305840 | 0.88 | ACHE (0.44) | — | |
| SCHEMBL7314325 | 0.87 | ALDH1A1 (0.43) | SIGMAR1TMEM97ABCB1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |