Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | REN | P00797 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31407581 | 0.91 | CTSL (0.64) | CCKBRCTSLCTSSCTSKTP53 | |
| SCHEMBL19166875 | 0.91 | CTSL (0.64) | CCKBRCTSLCTSSCTSKTP53 | |
| SCHEMBL27902206 | 0.91 | CCKBR (0.71) | CCKBRCTSLCTSSCTSKREN | |
| SCHEMBL27902208 | 0.91 | CCKBR (0.71) | CCKBRCTSLCTSSCTSKREN | |
| SCHEMBL30597905 | 0.89 | CCKBR (0.71) | CCKBRCTSLCTSSCTSKREN | |
| SCHEMBL9787805 | 0.89 | CCKBR (0.71) | CCKBRCTSLCTSSCTSKREN | |
| SCHEMBL9787712 | 0.86 | CCKBR (0.76) | CCKBRCTSLCTSSCTSKREN | |
| SCHEMBL30762270 | 0.86 | CCKBR (0.70) | CCKBRCTSLCTSSCTSKREN | |
| SCHEMBL11236267 | 0.86 | CCKBR (0.65) | CCKBRCTSLCTSSCTSKREN | |
| SCHEMBL11236250 | 0.86 | CCKBR (0.65) | CCKBRCTSLCTSSCTSKREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691985-B1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMA INC (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5608078-A | Phosphonomethyldipeptides and process for preparation thereof | MERRELL PHARMACEUTICALS INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0618224-A1 | Phosphonomethyldipeptides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-05 | — | — | EP | disclosed |