Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.51 |
| ▸ | MMP13 | P45452 | 13/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 10/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138714 | 0.94 | MMP1 (0.58) | MMP1MMP13ADAM17ADAMTS4MMP2 | |
| SCHEMBL7134721 | 0.91 | MMP1 (0.52) | MMP1MMP13ADAM17ADAMTS4MMP2 | |
| SCHEMBL7144691 | 0.91 | MMP1 (0.45) | MMP1MMP13ADAM17ADAMTS4MMP2 | |
| SCHEMBL7315160 | 0.89 | MMP1 (0.52) | MMP1MMP13ADAM17ADAMTS4MMP2 | |
| SCHEMBL7143931 | 0.87 | MMP1 (0.52) | MMP1MMP13ADAM17MMP2 | |
| SCHEMBL7141581 | 0.85 | MMP1 (0.59) | MMP1MMP13ADAM17ADAMTS4MMP2 | |
| SCHEMBL7302665 | 0.85 | MMP1 (0.53) | MMP1MMP13ADAM17MMP2 | |
| SCHEMBL7139217 | 0.83 | MMP13 (0.53) | MMP1MMP13ADAM17MMP2 | |
| SCHEMBL7137874 | 0.82 | MMP1 (0.46) | MMP1MMP13ADAM17ADAMTS4MMP2 | |
| SCHEMBL7140721 | 0.82 | MMP13 (0.43) | MMP1MMP13ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214870-B1 | ANTIARTHRITIC AGENTS; ANTICANCER AGENTS | PFIZER INC | 2001-04-10 | — | — | US | disclosed |
| EP-1041072-A1 | Dioxocyclopentyl hydroxamic acids | Pfizer Products Inc. (US) | 2000-10-04 | — | — | EP | disclosed |