Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312898 | 0.83 | RAB9A (0.67) | ALDH1A1LMNAPOLBKDM4EMEN1 | |
| SCHEMBL25247976 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTPOLBGAA | |
| SCHEMBL14720666 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTPOLBGAA | |
| SCHEMBL28570849 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTPOLBGAA | |
| SCHEMBL28394623 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTPOLBGAA | |
| SCHEMBL8407368 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTPOLBGAA | |
| SCHEMBL11360223 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTPOLBGAA | |
| SCHEMBL16453447 | 0.81 | HSD11B1 (0.50) | ALDH1A1LMNAMAPTPOLBMEN1 | |
| SCHEMBL28088696 | 0.81 | POLB (0.50) | ALDH1A1LMNAMAPTPOLBGAA | |
| SCHEMBL6430908 | 0.80 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |