Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096734 | 0.89 | PPARG (0.42) | MTNR1ACYP11B2MCHR1ALDH1A1KDM4E | |
| SCHEMBL6949352 | 0.87 | AKR1C2 (0.47) | MTNR1ACYP11B2MCHR1ALDH1A1KDM4E | |
| SCHEMBL7071372 | 0.83 | PPARG (0.41) | MTNR1AALDH1A1HPGDNPC1POLB | |
| SCHEMBL11459008 | 0.81 | CFTR (0.39) | ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL7308736 | 0.79 | MAOB (0.51) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL8533789 | 0.78 | CYP11B2 (0.45) | MTNR1ACYP11B2ALOX5CYP11B1 | |
| SCHEMBL11468480 | 0.78 | GAA (0.34) | MCHR1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL7310496 | 0.78 | NPC1 (0.49) | ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL11468496 | 0.76 | MCHR1 (0.41) | CYP11B2MCHR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL7305877 | 0.76 | NPC1 (0.41) | ALDH1A1KDM4EHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |