Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.43 |
| ▸ | HTR3A | P46098 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7303177 | 0.99 | TFPI2 (0.44) | TFPI2CHRM3CHRM2CHRM1HTR3A | |
| SCHEMBL7267718 | 0.78 | ALDH1A1 (0.55) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7443261 | 0.77 | ALDH1A1 (0.54) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL4917433 | 0.72 | HTR3E (0.56) | CHRM3CHRM2CHRM1HTR3AHTR3E | |
| SCHEMBL4917429 | 0.72 | HTR3E (0.56) | CHRM3CHRM2CHRM1HTR3AHTR3E | |
| SCHEMBL3779323 | 0.71 | CHRM3 (0.49) | CHRM3CHRM2CHRM1HTR3AHTR3E | |
| SCHEMBL13134299 | 0.71 | CHRM3 (0.49) | CHRM3CHRM2CHRM1HTR3AHTR3E | |
| SCHEMBL9601383 | 0.70 | ALDH1A1 (0.54) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL27887683 | 0.69 | TFPI2 (0.51) | TFPI2ALDH1A1MEN1KMT2A | |
| SCHEMBL10567044 | 0.68 | CHRM3 (0.43) | CHRM3CHRM2CHRM1HTR3AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403882-A2 | Indole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |