Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389056 | 0.80 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL2023306 | 0.80 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL9234732 | 0.75 | MEN1 (0.54) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL9231524 | 0.75 | KMT2A (0.54) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL3390578 | 0.75 | GRIN2D (0.51) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL2052079 | 0.72 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL29530611 | 0.72 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL28038339 | 0.71 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL3198 | 0.70 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL7306652 | 0.70 | NQO2 (0.61) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |