Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946227 | 0.82 | SIGMAR1 (0.67) | SIGMAR1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL7294524 | 0.80 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL9472044 | 0.80 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1KDM4EHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL9470759 | 0.79 | SIGMAR1 (0.54) | SIGMAR1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL7305898 | 0.79 | SIGMAR1 (0.77) | SIGMAR1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL8946216 | 0.78 | SIGMAR1 (0.65) | SIGMAR1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL7299921 | 0.78 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL8946225 | 0.78 | SIGMAR1 (0.75) | SIGMAR1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17237763 | 0.78 | SIGMAR1 (0.75) | SIGMAR1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL7299989 | 0.78 | SIGMAR1 (0.75) | SIGMAR1ALDH1A1KDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0580503-B1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |