SCHEMBL7306314

SCHEMBL7306314

O=C(C1CCc2ccccc2C1)C1C(=S)CN[C@@H]1C(=O)C1CCN[C@@H]1C(O)=S

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.33
IDH1 O75874 1/20 0.32
P2RX7 Q99572 1/20 0.31
GHSR Q92847 1/20 0.31
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30
PLD2 O14939 1/20 0.30
PLD1 Q13393 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9049843 1.00 FAAH (0.33) FAAHIDH1P2RX7GHSRMTNR1A
SCHEMBL9048597 1.00 FAAH (0.33) FAAHIDH1P2RX7GHSRMTNR1A
SCHEMBL9049941 0.94 MEN1 (0.30)
SCHEMBL8153391 0.84 PREP (0.34)
SCHEMBL9175911 0.84 PREP (0.34)
SCHEMBL7301200 0.84 FAAH (0.38) FAAHIDH1P2RX7GHSRMTNR1A
SCHEMBL9050007 0.83 GBA1 (0.32)
SCHEMBL9047518 0.83 GBA1 (0.32)
SCHEMBL7294072 0.82
SCHEMBL9051048 0.81 GBA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed