SCHEMBL9049941

SCHEMBL9049941

O=C(C1Cc2ccccc2C1)C1C(=S)CN[C@@H]1C(=O)C1CCN[C@@H]1C(O)=S

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SLC1A2 P43004 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9049843 0.94 FAAH (0.33)
SCHEMBL9048597 0.94 FAAH (0.33)
SCHEMBL7306314 0.94 FAAH (0.33)
SCHEMBL7294072 0.85
SCHEMBL9048296 0.83 KMT2A (0.31) KMT2A
SCHEMBL8153391 0.82 PREP (0.34)
SCHEMBL9050045 0.82 PREP (0.30)
SCHEMBL9175911 0.82 PREP (0.34)
SCHEMBL9049794 0.80 GBA1 (0.31)
SCHEMBL9050007 0.80 GBA1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0536399-B1 NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME ZERIA PHARM CO LTD (JP) 1996-01-24 EP disclosed
US-5407950-A Brain disorders, senile dementia ZERIA PHARMACEUTICAL CO., LTD. (JP) 1995-04-18 US disclosed
EP-0536399-A1 NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME ZERIA PHARMACEUTICAL CO., LTD. (JP) 1993-04-14 EP disclosed