Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119146 | 0.85 | APAF1 (0.56) | APAF1BCHEANPEPMTNR1AMTNR1B | |
| SCHEMBL9119155 | 0.85 | APAF1 (0.56) | APAF1BCHEANPEPMTNR1AMTNR1B | |
| SCHEMBL10767549 | 0.83 | CASR (0.59) | MTNR1AMTNR1B | |
| SCHEMBL7317181 | 0.83 | APAF1 (0.46) | APAF1BCHEBCAT2ANPEPALOX5 | |
| SCHEMBL7318383 | 0.83 | APAF1 (0.46) | APAF1BCHEBCAT2ANPEPALOX5 | |
| SCHEMBL8083546 | 0.80 | ERAP2 (0.45) | APAF1BCHEBCAT2MTNR1AMTNR1B | |
| SCHEMBL1790979 | 0.76 | SCN9A (0.57) | — | |
| SCHEMBL411692 | 0.76 | SCN9A (0.57) | — | |
| Hydrochloric Acid SCHEMBL4231798 | 0.76 | APAF1 (0.43) | APAF1BCHEANPEPMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL5966887 | 0.75 | SCN9A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |