Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP14 | P50281 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | FCER2 | P06734 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319574 | 0.88 | CASR (0.53) | ERAP2ERAP1LNPEPMMP9MMP14 | |
| SCHEMBL7306322 | 0.80 | APAF1 (0.49) | APAF1BCHEMTNR1AMTNR1BBCAT2 | |
| SCHEMBL7310003 | 0.80 | MMP1 (0.39) | ERAP2ERAP1LNPEPMMP9MMP1 | |
| SCHEMBL30164272 | 0.80 | GGT1 (0.55) | ERAP2ERAP1LNPEPMMEMMP1 | |
| SCHEMBL1792753 | 0.79 | PSMB5 (0.54) | MMP8MMEALDH1A1MMP1FCER2 | |
| SCHEMBL1792750 | 0.79 | PSMB5 (0.54) | MMP8MMEALDH1A1MMP1FCER2 | |
| SCHEMBL7317031 | 0.79 | MMP9 (0.46) | ERAP2ERAP1LNPEPMMP9MMP14 | |
| Hydrochloric Acid SCHEMBL30164377 | 0.79 | GGT1 (0.54) | ERAP2ERAP1LNPEPMMEMMP1 | |
| Hydrochloric Acid SCHEMBL30164236 | 0.79 | GGT1 (0.54) | ERAP2ERAP1LNPEPMMEMMP1 | |
| SCHEMBL7317844 | 0.78 | GAA (0.43) | ALDH1A1LMNAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |