Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312245 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BALDH1A1MCHR1 | |
| Hydrochloric Acid SCHEMBL23361868 | 0.84 | CYP4F2 (0.44) | CYP4F2CYP4A11ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8327234 | 0.80 | MCHR1 (0.44) | CYP4F2CYP4A11ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7297755 | 0.80 | ITGB3 (0.59) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7308603 | 0.79 | ITGB3 (0.66) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7312182 | 0.78 | MCHR1 (0.54) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7307341 | 0.78 | ITGB3 (0.50) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7295945 | 0.78 | MCHR1 (0.45) | ITGB3ITGA2BMCHR1ADRB3 | |
| SCHEMBL7788810 | 0.77 | ITGB3 (0.58) | CYP4F2CYP4A11ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7309480 | 0.77 | ITGB3 (0.66) | ITGB3ITGA2BMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |