Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306419 | 0.88 | CYP4F2 (0.45) | ITGB3ITGA2BMCHR1ALDH1A1 | |
| SCHEMBL18799732 | 0.83 | NAMPT (0.47) | ITGB3ITGA2BNAMPTOPRD1CHRNB2 | |
| SCHEMBL7297755 | 0.80 | ITGB3 (0.59) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7308603 | 0.79 | ITGB3 (0.66) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL5548043 | 0.79 | DRD2 (0.45) | NAMPTCHRNB2CHRNA4MCHR1 | |
| SCHEMBL7312182 | 0.78 | MCHR1 (0.54) | ITGB3ITGA2BNAMPTMCHR1 | |
| SCHEMBL6195819 | 0.77 | MCHR1 (0.45) | ITGB3ITGA2BNAMPTOPRD1CHRNB2 | |
| SCHEMBL6195823 | 0.77 | MCHR1 (0.45) | ITGB3ITGA2BNAMPTOPRD1CHRNB2 | |
| SCHEMBL10253259 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL354268 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |