Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316593 | 0.89 | KCNA5 (0.38) | KCNA5HDAC1MCL1ALDH1A1CYP1A2 | |
| SCHEMBL7311363 | 0.83 | KCNA5 (0.41) | KCNA5HDAC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7313662 | 0.83 | KCNA5 (0.46) | KCNA5KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7317323 | 0.83 | KCNA5 (0.45) | KCNA5HDAC1GAAKDM4EALDH1A1 | |
| SCHEMBL7320073 | 0.82 | PDE3B (0.52) | HDAC1GAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7311398 | 0.79 | HSD11B1 (0.41) | KCNA5MCL1ALDH1A1 | |
| SCHEMBL7306355 | 0.78 | KCNA5 (0.40) | KCNA5HDAC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7308692 | 0.77 | KCNA5 (0.51) | KCNA5GAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7309212 | 0.76 | PDE3B (0.43) | KCNA5GAAKDM4EALDH1A1 | |
| SCHEMBL7312280 | 0.76 | PDE3B (0.46) | PPARGPPARDPPARAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |