Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984241 | 0.82 | CYP1A2 (0.52) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL8225071 | 0.79 | L3MBTL1 (0.47) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL5373491 | 0.78 | MCHR1 (0.40) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL8227403 | 0.78 | L3MBTL1 (0.43) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL2051019 | 0.78 | CYP1A2 (0.50) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL1837034 | 0.78 | ESR1 (0.49) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL7308195 | 0.77 | LMNA (0.48) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL1836896 | 0.76 | ESR1 (0.51) | LMNAMAPTALDH1A1MEN1NR1I2 | |
| SCHEMBL1836823 | 0.76 | ESR1 (0.51) | LMNAMAPTALDH1A1MEN1NR1I2 | |
| SCHEMBL1842346 | 0.76 | ESR1 (0.51) | LMNAMAPTALDH1A1MEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |