Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303879 | 0.90 | KDM4E (0.43) | LMNAMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL1984241 | 0.85 | CYP1A2 (0.52) | LMNAMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL7930638 | 0.79 | CYP1A2 (0.57) | LMNAMAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL2051019 | 0.77 | CYP1A2 (0.50) | LMNAMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL7306616 | 0.77 | LMNA (0.42) | LMNAMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL1238407 | 0.77 | LMNA (0.60) | LMNAMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL24608167 | 0.76 | CYP1A2 (0.52) | LMNAMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL4961675 | 0.76 | KDM4E (0.44) | LMNAMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL8220033 | 0.76 | ALDH1A1 (0.44) | LMNAMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL5250022 | 0.76 | LMNA (0.44) | LMNAMAPTKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |