Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318358 | 0.82 | FFAR4 (0.38) | BACE1 | |
| SCHEMBL7309814 | 0.79 | ALDH1A1 (0.38) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7309620 | 0.78 | TAAR1 (0.36) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7308779 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL30750277 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL7314258 | 0.71 | CHRM2 (0.37) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7310024 | 0.70 | POLB (0.33) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7316634 | 0.69 | ALDH1A1 (0.39) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7317206 | 0.68 | ALDH1A1 (0.41) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7307228 | 0.67 | EBP (0.55) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |