Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 5/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313549 | 0.82 | PTGER4 (0.39) | KMT2A | |
| SCHEMBL7309814 | 0.81 | ALDH1A1 (0.38) | KMT2ACHRM3CHRM2CHRM1LMNA | |
| SCHEMBL7309620 | 0.77 | TAAR1 (0.36) | FAAHCHRM3CHRM2CHRM1LMNA | |
| SCHEMBL7314258 | 0.75 | CHRM2 (0.37) | POLBKMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL7317206 | 0.70 | ALDH1A1 (0.41) | KMT2ACHRM3CHRM2CHRM1LMNA | |
| SCHEMBL7306684 | 0.70 | BACE1 (0.31) | CHRM3CHRM2CHRM1 | |
| SCHEMBL7316634 | 0.68 | ALDH1A1 (0.39) | KMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL7317285 | 0.68 | CHRM3 (0.33) | FAAHCHRM3CHRM2CHRM1LMNA | |
| SCHEMBL7307228 | 0.66 | EBP (0.55) | KMT2ACHRM3CHRM2CHRM1LMNA | |
| SCHEMBL7308779 | 0.65 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |