Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309814 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHRMEN1KMT2ASIGMAR1 | |
| SCHEMBL8236160 | 0.78 | MEN1 (0.49) | ALDH1A1MEN1KMT2AATMSIGMAR1 | |
| SCHEMBL7307109 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TSHRMEN1KMT2AATM | |
| SCHEMBL8837045 | 0.77 | SIGMAR1 (0.50) | ALDH1A1TSHRSIGMAR1CHRM3CHRM2 | |
| SCHEMBL7307228 | 0.76 | EBP (0.55) | TSHRMEN1KMT2ASIGMAR1CHRM3 | |
| SCHEMBL7309620 | 0.76 | TAAR1 (0.36) | ALDH1A1TSHRSIGMAR1CHRM3CHRM2 | |
| SCHEMBL7317285 | 0.75 | CHRM3 (0.33) | ALDH1A1TSHRCHRM3CHRM2CHRM1 | |
| SCHEMBL7374836 | 0.74 | MEN1 (0.47) | ALDH1A1MEN1KMT2AATMSIGMAR1 | |
| SCHEMBL7304839 | 0.74 | CACNA1G (0.44) | ALDH1A1 | |
| SCHEMBL7310042 | 0.73 | FAAH (0.32) | ALDH1A1TSHRCHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |