Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313168 | 0.76 | TSHR (0.49) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL31669620 | 0.76 | KDM4E (0.45) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7317057 | 0.76 | RAB9A (0.44) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4779545 | 0.72 | RAB9A (1.00) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL17541018 | 0.69 | KDM4E (0.46) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7317792 | 0.69 | ALDH1A3 (0.54) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL2251442 | 0.69 | JAK2 (0.70) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL3236843 | 0.68 | RAB9A (0.45) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5340648 | 0.66 | RAB9A (0.49) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL12970469 | 0.66 | USP7 (0.43) | MAPTCHEK1DAPK3ABL1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596872-A | Imidazo[1,2-a]pyridines, and process for their preparation | SCHERING A.G. (DE) | 1986-06-24 | — | — | US | claimed |
| US-4596872-A | Imidazo[1,2-a]pyridines, and process for their preparation | SCHERING A.G. (DE) | 1986-06-24 | — | — | US | disclosed |