Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4798554 | 0.84 | NPC1 (1.00) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7499663 | 0.76 | ALDH1A1 (0.61) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL4727113 | 0.76 | MEN1 (0.60) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL30168190 | 0.74 | RAB9A (0.59) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL19748096 | 0.73 | KDM4E (0.57) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7306815 | 0.72 | NPC1 (0.56) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL2519357 | 0.69 | KDM4E (0.53) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7929892 | 0.67 | FLT3 (0.58) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL5340648 | 0.66 | RAB9A (0.49) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL5478856 | 0.66 | RAB9A (0.49) | RAB9AALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |