Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298730 | 0.75 | KDM4E (0.54) | MAPTNPC1RAB9AMCHR1MEN1 | |
| Hydrochloric Acid SCHEMBL7323352 | 0.74 | KDM4E (0.53) | MAPTNPC1RAB9AMCHR1MEN1 | |
| Hydrochloric Acid SCHEMBL7307645 | 0.73 | TNF (0.40) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8841261 | 0.71 | ITGB3 (0.57) | — | |
| SCHEMBL2836025 | 0.70 | SMN1; SMN2 (0.70) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL20535966 | 0.69 | MAPT (0.55) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL7306495 | 0.69 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL7328382 | 0.69 | ITGB3 (0.47) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL7395413 | 0.69 | MAPT (0.43) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL6949063 | 0.68 | ITGB3 (0.56) | MAPTNPC1RAB9ASMN1; SMN2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |