Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | POLA1 | P09884 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306237 | 0.90 | MTNR1A (0.45) | MTNR1ANOTUMHSD17B10MTNR1BALDH1A1 | |
| SCHEMBL8742789 | 0.85 | MTNR1A (0.48) | MTNR1ANOTUMHSD17B10MTNR1BAGTR2 | |
| SCHEMBL7305955 | 0.85 | MTNR1A (0.48) | MTNR1ANOTUMHSD17B10MTNR1BAGTR2 | |
| SCHEMBL8742853 | 0.77 | MTNR1A (0.47) | MTNR1ANOTUMHSD17B10MTNR1BALDH1A1 | |
| SCHEMBL7316234 | 0.77 | MTNR1A (0.47) | MTNR1ANOTUMHSD17B10MTNR1BALDH1A1 | |
| SCHEMBL8742926 | 0.77 | MTNR1A (0.47) | MTNR1ANOTUMHSD17B10MTNR1BALDH1A1 | |
| SCHEMBL7343587 | 0.76 | NOTUM (0.50) | MTNR1ANOTUMHSD17B10MTNR1BAGTR2 | |
| SCHEMBL7343593 | 0.76 | NOTUM (0.50) | MTNR1ANOTUMHSD17B10MTNR1BAGTR2 | |
| SCHEMBL11047749 | 0.72 | ACE (0.45) | MTNR1ANOTUMHSD17B10MTNR1BAGTR2 | |
| SCHEMBL8742995 | 0.71 | NOTUM (0.45) | MTNR1ANOTUMHSD17B10MTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699680-B1 | Oxazoloquinolinone derivatives, their preparation and their use in therapy | SANOFI SYNTHELABO (FR) | 2000-03-08 | — | — | EP | claimed |