Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204538 | 0.70 | TDP2 (0.46) | GSK3BKMT2AMEN1MAPTCACNA1C | |
| SCHEMBL7307161 | 0.67 | KMT2A (0.42) | GSK3BKMT2APKMHPGDMEN1 | |
| SCHEMBL1398948 | 0.66 | RPS6KA2 (0.51) | KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11012599 | 0.66 | MAPK1 (0.45) | KMT2APKMHPGDMEN1MAPT | |
| SCHEMBL11012601 | 0.66 | MAPK1 (0.45) | KMT2APKMHPGDMEN1MAPT | |
| SCHEMBL28511582 | 0.66 | KMT2A (0.49) | KMT2APKMHPGDMEN1NPC1 | |
| SCHEMBL5579243 | 0.65 | TTR (0.53) | KMT2APKMHPGDMEN1NPC1 | |
| SCHEMBL522710 | 0.64 | PIN1 (0.62) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6987302 | 0.63 | KMT2A (0.53) | KMT2APKMHPGDMEN1NPC1 | |
| SCHEMBL14508734 | 0.63 | KMT2A (0.53) | KMT2APKMHPGDMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477446-A | ANTIALLERGENS | USV PHARMACEUTICAL CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |