Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 10/20 | 0.39 |
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309077 | 1.00 | CACNA1B (0.40) | CACNA1BDRD2DRD3FKBP1AEBP | |
| SCHEMBL7316567 | 0.81 | FKBP1A (0.48) | FKBP1ACHRM3 | |
| SCHEMBL7306123 | 0.81 | CFD (0.47) | CACNA1BFKBP1A | |
| SCHEMBL7316569 | 0.79 | PRCP (0.45) | FKBP1ACHRM3PRCP | |
| SCHEMBL7305475 | 0.78 | FKBP1A (0.53) | FKBP1A | |
| SCHEMBL7305485 | 0.78 | FKBP1A (0.53) | FKBP1A | |
| SCHEMBL7308557 | 0.77 | CHRM3 (0.44) | FKBP1ACHRM3 | |
| SCHEMBL7308546 | 0.77 | CHRM3 (0.44) | FKBP1ACHRM3 | |
| SCHEMBL7309531 | 0.77 | FKBP1A (0.51) | FKBP1AEBPSIGMAR1PRCP | |
| SCHEMBL7309517 | 0.77 | FKBP1A (0.51) | FKBP1AEBPSIGMAR1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |