Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312566 | 0.85 | SMN1; SMN2 (0.43) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7316430 | 0.84 | SMN1; SMN2 (0.42) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10374595 | 0.80 | LMNA (0.45) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10376143 | 0.78 | SMN1; SMN2 (0.39) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10374618 | 0.77 | ALDH1A1 (0.37) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7307522 | 0.73 | MAPT (0.35) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7317738 | 0.73 | MEN1 (0.49) | KMT2AALDH1A1POLBMEN1KDM4E | |
| SCHEMBL7317948 | 0.73 | KDM4E (0.39) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7309468 | 0.73 | ALDH1A1 (0.37) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10374591 | 0.73 | KDM4E (0.40) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |