Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | G6PD | P11413 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879713 | 0.83 | ALDH1A1 (1.00) | MAPTALDH1A1HTTHPGDG6PD | |
| Hydrochloric Acid SCHEMBL9320078 | 0.81 | ALDH1A1 (0.96) | MAPTALDH1A1HTTHPGDG6PD | |
| SCHEMBL2808252 | 0.81 | ALDH1A1 (0.70) | MAPTALDH1A1HTTHPGDG6PD | |
| SCHEMBL5593649 | 0.81 | ALDH1A1 (0.65) | MAPTALDH1A1HTTHPGDG6PD | |
| Hydrochloric Acid SCHEMBL11708748 | 0.80 | ALDH1A1 (0.93) | MAPTALDH1A1HTTHPGDG6PD | |
| SCHEMBL9321009 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1HTTHPGDG6PD | |
| SCHEMBL5917427 | 0.75 | ALDH1A1 (0.67) | MAPTALDH1A1HTTHPGDG6PD | |
| SCHEMBL3655957 | 0.75 | ALDH1A1 (0.57) | MAPTALDH1A1HTTHPGDG6PD | |
| Chloroacetic Acid SCHEMBL9321136 | 0.74 | ALDH1A1 (0.81) | MAPTALDH1A1HTTHPGDG6PD | |
| SCHEMBL9132029 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1HTTHPGDG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594257-B1 | 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP INC (US) | 1996-07-10 | — | — | EP | disclosed |