SCHEMBL9132029

SCHEMBL9132029

O=c1ccsn1Cc1ccc(Cl)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
HTT P42858 3/20 0.51
TDP1 Q9NUW8 3/20 0.51
HPGD P15428 3/20 0.51
MAPT P10636 2/20 0.51
G6PD P11413 2/20 0.51
ALOX15 P16050 2/20 0.51
HSD17B10 Q99714 2/20 0.51
PKM P14618 1/20 0.51
LMNA P02545 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
CYP2A13 Q16696 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 3/20 0.42
POLB P06746 1/20 0.42
MEN1 O00255 1/20 0.42
JAK2 O60674 1/20 0.42
KMT2A Q03164 1/20 0.42
PAX8 Q06710 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9320144 0.80 ALDH1A1 (0.64) ALDH1A1HTTTDP1HPGDMAPT
SCHEMBL9131508 0.79 ALDH1A1 (0.53) ALDH1A1HTTTDP1HPGDMAPT
SCHEMBL2808252 0.78 ALDH1A1 (0.70) ALDH1A1HTTTDP1HPGDMAPT
SCHEMBL5917447 0.77 SMN1; SMN2 (0.53) ALDH1A1HTTTDP1HPGDMAPT
SCHEMBL9321009 0.72 ALDH1A1 (0.62) ALDH1A1HTTTDP1HPGDMAPT
SCHEMBL2179428 0.70 DBH (0.53) ALDH1A1HTTHPGDMAPTPKM
SCHEMBL7563897 0.69 CA12 (0.51) HTTTDP1LMNANPC1RAB9A
SCHEMBL4749291 0.69 CA12 (0.51) HTTTDP1LMNANPC1RAB9A
SCHEMBL9130618 0.68 KAT2B (0.53) ALDH1A1HTTMAPTG6PDKDM4E
SCHEMBL7628912 0.68 ALDH1A1 (0.51) ALDH1A1HTTTDP1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US claimed
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US disclosed
EP-0331319-B1 Method for the formation of images KONISHIROKU PHOTO IND (JP) 1994-01-26 EP disclosed
US-H1090-H High contrast; hydrazide, isothizolone, bromonitroalcohol KONICA CORPORATION (JP) 1992-08-04 US disclosed
EP-0356801-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1990-03-07 EP disclosed
EP-0147970-B1 MICROBIOCIDAL OR ANTIMICROBIAL BIOMEDICAL DEVICES ROHM AND HAAS COMPANY (US) 1989-03-01 EP disclosed
EP-0090584-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1986-12-03 EP disclosed
US-4542169-A Biomedical devices containing isothiazolones to control bacteria growth ROHM AND HAAS COMPANY (US) 1985-09-17 US disclosed
EP-0147970-A1 Microbiocidal or antimicrobial biomedical devices ROHM AND HAAS COMPANY (US) 1985-07-10 EP disclosed
US-4490462-A CONTAINING ISOTHIAZOLIN-3-ONE MICROBIOCIDE OR FUNGICIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-12-25 US disclosed
US-4325201-A BACTERICIDES, FUNGICIDES, PESTICIDES, AND SLIMICIDES; PAINTS; PRESERVATIVES ROHM AND HAAS COMPANY (US) 1982-04-20 US disclosed
US-4322475-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1982-03-30 US disclosed
US-4279762-A Cutting oils containing 3-isothiazolones as biocides ROHM AND HAAS COMPANY (US) 1981-07-21 US disclosed
US-4265899-A FUNGICIDES, BACTERICIDES ROHM AND HAAS COMPANY (US) 1981-05-05 US disclosed
US-4252694-A MICROBIOCIDES ROHM AND HAAS COMPANY (US) 1981-02-24 US disclosed
US-4243403-A BACTERICIDES, ACRYLIC POLYMERS, FUNGICIDES ROHM AND HAAS COMPANY (US) 1981-01-06 US disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4105431-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1978-08-08 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed