Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360095 | 0.77 | ALDH1A1 (0.35) | DPP4 | |
| SCHEMBL20825317 | 0.72 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2DPP4DPP8 | |
| SCHEMBL23616302 | 0.72 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2DPP4DPP8 | |
| SCHEMBL10068278 | 0.72 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2DPP4DPP8 | |
| Leucine SCHEMBL1452794 | 0.70 | SLC7A5 (0.64) | SLC7A5SLC1A3SLC1A2DPP7RNPEP | |
| SCHEMBL1152947 | 0.70 | OPRK1 (0.30) | — | |
| SCHEMBL811779 | 0.70 | TSHR (0.36) | — | |
| Cyclohexane SCHEMBL9122052 | 0.70 | TSHR (0.36) | — | |
| SCHEMBL10535546 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL10535530 | 0.69 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |