Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301234 | 0.88 | ITGB3 (0.36) | ALDH1A1MAPTITGB3ITGA2BMEN1 | |
| SCHEMBL7307568 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MAPTITGB3ITGA2BDRD2 | |
| SCHEMBL7299589 | 0.84 | MCHR1 (0.39) | ALDH1A1MAPTITGB3ITGA2BDRD2 | |
| SCHEMBL7306382 | 0.84 | ITGB3 (0.36) | ALDH1A1MAPTITGB3ITGA2BDRD2 | |
| SCHEMBL7392614 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTITGB3ITGA2BDRD3 | |
| SCHEMBL7308655 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7308658 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7307578 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPTITGB3ITGA2BDRD2 | |
| SCHEMBL7298306 | 0.78 | ITGB3 (0.54) | ALDH1A1MAPTITGB3ITGA2B | |
| SCHEMBL7298312 | 0.78 | ITGB3 (0.54) | ALDH1A1MAPTITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |