Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301234 | 0.95 | ITGB3 (0.36) | ITGB3ITGA2BKDM4EMEN1MAPT | |
| SCHEMBL7311917 | 0.85 | MAPT (0.43) | ITGB3ITGA2BKDM4EMAPTKMT2A | |
| SCHEMBL7306377 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BMCHR1DRD2DRD3 | |
| SCHEMBL7318519 | 0.84 | ITGB3 (0.33) | ITGB3ITGA2BKDM4EMEN1MAPT | |
| SCHEMBL7307574 | 0.84 | ALDH1A1 (0.35) | ITGB3ITGA2BMEN1MAPTKMT2A | |
| SCHEMBL7311321 | 0.84 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL7298306 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7308658 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7298312 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7308655 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |