Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132093 | 1.00 | CES2 (0.57) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL10589346 | 1.00 | CES2 (0.57) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL440884 | 0.98 | CES2 (0.54) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL7916146 | 0.91 | CES1 (0.46) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL11509841 | 0.89 | CES2 (0.64) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL2989445 | 0.89 | CES2 (0.64) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL844786 | 0.86 | CES2 (0.61) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL10996023 | 0.83 | CES2 (0.53) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL10360944 | 0.83 | CES2 (0.57) | CES2MEN1KMT2A | |
| SCHEMBL8637203 | 0.83 | CES2 (0.57) | CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572952-A1 | 4-Benzylpiperidine derivatives, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1993-12-08 | — | — | EP | disclosed |