SCHEMBL440884

SCHEMBL440884

CCCCCC(=O)C(C)C(C)=O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.54
MEN1 O00255 1/20 0.50
FAAH O00519 1/20 0.50
MAPK1 P28482 1/20 0.50
KMT2A Q03164 1/20 0.50
CES1 P23141 4/20 0.48
AKR1B1 P15121 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28132093 0.98 CES2 (0.57) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL7307626 0.98 CES2 (0.57) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL10589346 0.98 CES2 (0.57) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL7916146 0.93 CES1 (0.46) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL11509841 0.86 CES2 (0.64) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL2989445 0.86 CES2 (0.64) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL844786 0.84 CES2 (0.61) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL6860287 0.83 CES2 (0.41) CES2CES1
SCHEMBL18386280 0.82 LMNA (0.50) MEN1KMT2AAKR1B1
SCHEMBL3142041 0.82 CES2 (0.54) CES2MEN1FAAHMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12628862-B2 Liquid tobacco extract, method for making and aerosol-generating articles comprising such PHILIP MORRIS PRODUCTS S.A. (CH) 2026-05-19 US claimed
EP-4618781-A1 CONSUMABLE FOR AEROSOLISABLE FORMULATION Nicoventures Trading Limited (GB) 2025-09-24 EP claimed
EP-4618780-A1 CONSUMABLE FOR AEROSOLISABLE FORMULATION Nicoventures Trading Limited (GB) 2025-09-24 EP claimed
EP-4538307-A1 POLYOLEFIN ELASTOMER AND USE THEREOF IN PHOTOVOLTAIC ENCAPSULATION FILM Wanhua Chemical Group Co., Ltd. (CN) 2025-04-16 EP claimed
WO-2025043950-A1 POLYOLEFIN ELASTOMER AND USE THEREOF IN PHOTOVOLTAIC ENCAPSULATION FILM 万华化学集团股份有限公司 2025-03-06 WO claimed
CN-113826741-B Flavor improving agent for tea beverage and method for producing the same 长谷川香料株式会社 2024-08-02 CN claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP claimed
WO-2024105407-A1 CONSUMABLE FOR AEROSOLISABLE FORMULATION Nicoventures Trading Limited (GB) 2024-05-23 WO claimed
WO-2024105406-A1 CONSUMABLE FOR AEROSOLISABLE FORMULATION Nicoventures Trading Limited (GB) 2024-05-23 WO claimed
CN-115105967-B Acid-resistant alkali-resistant nanofiltration membrane and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
EP-2111765-B1 Hoodia plant extract with improved flavor UNILEVER NV (NL) 2013-01-16 EP claimed
US-7923435-B2 Hoodia plant extract with improved flavor PHYTOPHARM PLC (GB) 2011-04-12 US claimed
EP-2111763-A1 Process of making hoodia plant extract with improved flavor UNILEVER N.V. (NL) 2009-10-28 EP claimed
EP-2111765-A1 Hoodia plant extract with improved flavor UNILEVER N.V. (NL) 2009-10-28 EP claimed
US-20090264376-A1 Hoodia plant extract with improved flavor CONOPCO, INC., D/B/A UNILEVER 2009-10-22 US claimed
US-20090263510-A1 Process of making Hoodia plant extract with improved flavor CONOPCO, INC., D/B/A UNILEVER 2009-10-22 US claimed
US-7182796-B2 Odorant for fuel gas SODA AROMATIC CO., LTD. (JP) 2007-02-27 US claimed
US-20050020479-A1 Odorant for fuel gas SODA AROMATIC CO., LTD. (JP) 2005-01-27 US claimed
EP-1457547-A1 ODORANT FOR FUEL GAS SODA AROMATIC COMPANY, LIMITED (JP) 2004-09-15 EP claimed
US-20030092599-A1 Fragrance and flavor compositions and fragrance- and flavor-added products TAKASAGO INTERNATIONAL CORPORATION 2003-05-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12628862-B2 Liquid tobacco extract, method for making and aerosol-generating articles comprising such NDUFB10, EXOSC10, NDUFB7 CES2 4307/4885MEN1 4550/4885FAAH 2823/4885
US-20090264376-A1 Hoodia plant extract with improved flavor NR3C2, NR3C1, NR5A1 CES2 2658/4885MEN1 3335/4885FAAH 2597/4885
US-20090263510-A1 Process of making Hoodia plant extract with improved flavor HSD17B7, CYP17A1, HSD17B2 CES2 1599/4885MEN1 2893/4885FAAH 3228/4885
US-20030092599-A1 Fragrance and flavor compositions and fragrance- and flavor-added products FAAH, KISS1R, DOHH CES2 1233/4885MEN1 1478/4885FAAH 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.