Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 18/20 | 0.55 |
| ▸ | PPARA | Q07869 | 15/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321720 | 1.00 | SRR (0.56) | SRRPPARGPPARA | |
| SCHEMBL7307706 | 1.00 | SRR (0.56) | SRRPPARGPPARA | |
| SCHEMBL14498310 | 0.88 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL16754029 | 0.85 | MEN1 (0.51) | SRRPPARGPPARA | |
| SCHEMBL8711993 | 0.85 | PPARG (0.44) | SRRPPARGPPARA | |
| SCHEMBL8711997 | 0.85 | PPARG (0.44) | SRRPPARGPPARA | |
| SCHEMBL2943750 | 0.85 | MEN1 (0.51) | SRRPPARGPPARA | |
| SCHEMBL6218135 | 0.84 | PPARG (0.48) | SRRPPARGPPARA | |
| SCHEMBL6515182 | 0.84 | PPARG (0.50) | SRRPPARGPPARA | |
| SCHEMBL7425913 | 0.84 | PPARG (0.50) | SRRPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290413-A1 | PYRIDINONE AND PYRIMIDINONE DERIVATIVES AS FACTOR XIA INHIBITORS | ONO Pharmaceutical Co., Ltd. (JP) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016067143-A1 | N-(2-ALKYLENEIMINO-3-PHENYLPROPYL)ACETAMIDE COMPOUNDS AND THEIR USE AGAINST PAIN AND PRURITUS VIA INHIBITION OF TRPA1 CHANNELS | PFIZER INC. (US) | 2016-05-06 | — | — | WO | disclosed |
| EP-0835109-A4 | PYRIDINONE-THROMBIN INHIBITORS | MERCK & CO INC (US) | 1999-02-03 | — | — | EP | disclosed |
| US-5744486-A | Pyridinone thrombin inhibitors | MERCK & CO., INC. (US) | 1998-04-28 | — | — | US | disclosed |
| EP-0835109-A1 | PYRIDINONE-THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1998-04-15 | — | — | EP | disclosed |
| US-5668289-A | Pyridinone thrombin inhibitors | MERCK & CO., INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1997001338-A1 | PYRIDINONE-THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1997-01-16 | — | — | WO | disclosed |