Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | CPA2 | P48052 | 1/20 | 0.44 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.44 |
| ▸ | EBP | Q15125 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 9/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307838 | 1.00 | F2 (0.47) | F2CPA1CPA2CPA4EBP | |
| SCHEMBL7301363 | 0.89 | FKBP1A (0.47) | F2EBPSIGMAR1MAPTKMT2A | |
| SCHEMBL7301358 | 0.89 | FKBP1A (0.47) | F2EBPSIGMAR1MAPTKMT2A | |
| SCHEMBL7305485 | 0.88 | FKBP1A (0.53) | F2 | |
| SCHEMBL7305475 | 0.88 | FKBP1A (0.53) | F2 | |
| SCHEMBL7309531 | 0.87 | FKBP1A (0.51) | F2EBPSIGMAR1 | |
| SCHEMBL7309517 | 0.87 | FKBP1A (0.51) | F2EBPSIGMAR1 | |
| SCHEMBL7309067 | 0.87 | ACE (0.41) | F2ACEACE2 | |
| SCHEMBL7308379 | 0.87 | TACR1 (0.44) | F2ACE | |
| SCHEMBL7308390 | 0.87 | TACR1 (0.44) | F2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |