Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.70 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.69 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.69 |
| ▸ | CTSB | P07858 | 3/20 | 0.68 |
| ▸ | CTSS | P25774 | 2/20 | 0.68 |
| ▸ | CTSL | P07711 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463603 | 0.90 | CTSK (0.72) | CTSKCAPN1CTSBCTSSCTSL | |
| SCHEMBL7614025 | 0.90 | CTSK (0.72) | CTSKCAPN1CTSBCTSSCTSL | |
| SCHEMBL10948717 | 0.88 | CYP1A2 (0.58) | CTSKCAPN1CAPN2CTSBCTSS | |
| SCHEMBL11517210 | 0.88 | CYP1A2 (0.58) | CTSKCAPN1CAPN2CTSBCTSS | |
| SCHEMBL10953796 | 0.88 | CYP1A2 (0.61) | CTSKCAPN1CAPN2CTSBCTSS | |
| SCHEMBL7612544 | 0.87 | CTSK (0.71) | CTSKCAPN1CTSBCTSSCTSL | |
| SCHEMBL7612532 | 0.87 | CTSK (0.71) | CTSKCAPN1CTSBCTSSCTSL | |
| SCHEMBL27279511 | 0.87 | CTSK (0.71) | CTSKCAPN1CTSBCTSSCTSL | |
| SCHEMBL7330463 | 0.87 | CTSL (0.67) | CTSKCAPN1CAPN2CTSBCTSS | |
| SCHEMBL25406813 | 0.84 | CTSK (0.77) | CTSKCAPN1CTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575844-B1 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | HOFFMANN LA ROCHE (CH) | 1998-01-21 | — | — | EP | disclosed |
| EP-0575844-A2 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1993-12-29 | — | — | EP | disclosed |