Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.67 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.67 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.67 |
| ▸ | CTSK | P43235 | 7/20 | 0.66 |
| ▸ | CTSS | P25774 | 2/20 | 0.66 |
| ▸ | CTSB | P07858 | 2/20 | 0.66 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796791 | 0.87 | CTSL (0.67) | CTSLCAPN1CTSKCTSSCTSB | |
| SCHEMBL7307837 | 0.87 | CTSK (0.70) | CTSLCAPN1CAPN2CTSKCTSS | |
| SCHEMBL8823918 | 0.85 | CTSK (0.77) | CTSLCAPN1CTSKCTSSCTSB | |
| SCHEMBL14148467 | 0.85 | CTSK (0.77) | CTSLCAPN1CTSKCTSSCTSB | |
| SCHEMBL20770085 | 0.85 | CTSK (0.77) | CTSLCAPN1CTSKCTSSCTSB | |
| SCHEMBL25406813 | 0.85 | CTSK (0.77) | CTSLCAPN1CTSKCTSSCTSB | |
| SCHEMBL2930262 | 0.85 | CTSK (0.77) | CTSLCAPN1CTSKCTSSCTSB | |
| SCHEMBL4872585 | 0.85 | CTSK (0.77) | CTSLCAPN1CTSKCTSSCTSB | |
| SCHEMBL5598102 | 0.84 | CTSK (0.78) | CTSLCAPN1CAPN2CTSKCTSS | |
| SCHEMBL5598105 | 0.84 | CTSK (0.78) | CTSLCAPN1CAPN2CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575844-B1 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | HOFFMANN LA ROCHE (CH) | 1998-01-21 | — | — | EP | disclosed |
| EP-0575844-A2 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1993-12-29 | — | — | EP | disclosed |