Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.50 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306559 | 0.86 | ITGB3 (0.55) | CYP26A1CYP26B1MCHR1PLAUNPC1 | |
| SCHEMBL7299756 | 0.85 | ITGB3 (0.47) | CYP26A1CYP26B1HPSEMCHR1PLAU | |
| SCHEMBL7299057 | 0.81 | ITGB3 (0.54) | PLAUPLGPLATKLKB1PRSS1 | |
| SCHEMBL7301801 | 0.75 | PLAU (0.48) | MCHR1PLAUNPC1NFKB1RAB9A | |
| SCHEMBL7309377 | 0.73 | PLAU (0.47) | MCHR1PLAUNPC1NFKB1RAB9A | |
| SCHEMBL24892329 | 0.72 | PLAU (0.69) | PLAUNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7301277 | 0.71 | ITGB3 (0.70) | PLAURAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7310729 | 0.71 | ITGB3 (0.77) | MCHR1 | |
| SCHEMBL7305850 | 0.70 | PLAU (0.47) | MCHR1PLAUNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5582526 | 0.69 | MCHR1 (0.49) | MCHR1NPC1RAB9AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |