Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.54 |
| ▸ | PLAU | P00749 | 6/20 | 0.50 |
| ▸ | PLG | P00747 | 5/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 4/20 | 0.45 |
| ▸ | PLAT | P00750 | 4/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306559 | 0.94 | ITGB3 (0.55) | ITGB3ITGA2BPLAUPLGKLKB1 | |
| SCHEMBL7299756 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BPLAU | |
| SCHEMBL7305850 | 0.88 | PLAU (0.47) | ITGB3ITGA2BPLAUPLGKLKB1 | |
| SCHEMBL7308827 | 0.86 | LMNA (0.47) | ITGB3ITGA2BPLAUPLGKLKB1 | |
| SCHEMBL7301801 | 0.83 | PLAU (0.48) | ITGB3ITGA2BPLAUPLGKLKB1 | |
| SCHEMBL7309377 | 0.81 | PLAU (0.47) | ITGB3ITGA2BPLAUF2PLAT | |
| SCHEMBL7307859 | 0.81 | CYP26A1 (0.50) | PLAUPLGKLKB1PRSS1PLAT | |
| SCHEMBL7299794 | 0.76 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1F2KLK1 | |
| SCHEMBL7430798 | 0.73 | PLAU (0.76) | ITGB3ITGA2BPLAUPLGKLKB1 | |
| Hydrochloric Acid SCHEMBL8994029 | 0.72 | F2 (0.71) | PLAUPLGKLKB1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |