Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306559 | 0.92 | ITGB3 (0.55) | ITGB3ITGA2BMCHR1PLAUCYP26A1 | |
| SCHEMBL7299057 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BPLAU | |
| SCHEMBL7307859 | 0.85 | CYP26A1 (0.50) | MCHR1PLAUCYP26A1CYP26B1NPC1 | |
| SCHEMBL7301801 | 0.81 | PLAU (0.48) | ITGB3ITGA2BMCHR1PLAUNPC1 | |
| SCHEMBL7309377 | 0.79 | PLAU (0.47) | ITGB3ITGA2BMCHR1PLAUNPC1 | |
| SCHEMBL7305850 | 0.78 | PLAU (0.47) | ITGB3ITGA2BMCHR1PLAUNPC1 | |
| SCHEMBL7308827 | 0.76 | LMNA (0.47) | ITGB3ITGA2BMCHR1PLAUSMN1; SMN2 | |
| SCHEMBL24891830 | 0.73 | KMT2A (0.64) | PLAUNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7307693 | 0.72 | ITGB3 (0.79) | ITGB3ITGA2BPLAUSMN1; SMN2TMPRSS2 | |
| SCHEMBL7300021 | 0.72 | ITGB3 (0.86) | ITGB3ITGA2BMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |